Gurobi uses system variables for multiple configuration purposes. For example, you can set the variable GRB_LICENSE_FILE to indicate where to look for a license file.
On Windows systems, environment variables are created and modified through the Control Panel. Searching for Environment Variables from the Control Panel search box will lead you to the appropriate screen. You will need to add a new System variable named GRB_LICENSE_FILE, and set it to the location of your license file (e.g., d:\gurobi\gurobi.lic). Important note: if your new environment variable is a User variable, this setting will only work for the current user.