Protein Folding Problem

Hone your modeling skills with this challenging Protein Folding problem. We’ll show you how to create a binary optimization model of the problem with the Gurobi Python API and then solve it using the Gurobi Optimizer.

This model is example 28 from the fifth edition of Model Building in Mathematical Programming by H. Paul Williams on pages 289-290 and 344-345.

This modeling example is at the advanced level, where we assume that you know Python and the Gurobi Python API and that you have advanced knowledge of building mathematical optimization models. Typically, the objective function and/or constraints of these examples are complex or require advanced features of the Gurobi Python API.